Expert Kidney Cancer
Treatment in Faridabad
Advanced renal cell carcinoma (RCC) treatment with sunitinib, pembrolizumab + axitinib, nivolumab + cabozantinib, and mTOR inhibitor therapy — by Dr. Novak Gupta, Senior Oncologist.
What is Kidney Cancer?
Kidney cancer — most commonly Renal Cell Carcinoma (RCC) — arises from the lining of the renal tubules. Clear cell RCC is the most frequent subtype (~75%) and is highly vascular, making anti-angiogenic (anti-VEGF) therapy particularly effective. Other subtypes include papillary, chromophobe, and collecting duct carcinoma. RCC is often discovered incidentally on imaging. The disease is notable for its response to immunotherapy and targeted agents, with combination immunotherapy-TKI regimens now producing remarkable outcomes in advanced disease.
Symptoms & Early Signs
Early recognition of symptoms leads to timely diagnosis and significantly better treatment outcomes. Do not ignore these warning signs.
Blood in Urine
Haematuria — visible or microscopic blood in urine — is the classic presenting symptom of kidney cancer.
Flank / Back Pain
Dull persistent pain in the flank or back on the affected side — often confused with musculoskeletal pain.
Palpable Abdominal Mass
A firm, non-tender lump felt in the flank or upper abdomen in large kidney tumours.
Paraneoplastic Fever
Unexplained persistent fever not due to infection — a paraneoplastic feature of renal cell carcinoma.
Weight Loss & Fatigue
Significant unexplained weight loss and anaemia-related fatigue are systemic symptoms of advanced RCC.
Hypertension
High blood pressure caused by tumour compression of renal vasculature or renin hypersecretion.
Causes & Risk Factors
Understanding risk factors helps in early detection and prevention. Consult Dr. Gupta if you are at elevated risk.
Smoking
Doubles kidney cancer risk — dose dependent relationship with duration and amount smoked.
Obesity
Excess body weight is one of the strongest modifiable risk factors for RCC, particularly in women.
Hypertension
Chronic high blood pressure and antihypertensive medications (especially diuretics) are associated risk factors.
VHL Syndrome
Von Hippel-Lindau hereditary syndrome causes multiple bilateral clear cell RCCs at a younger age.
Dialysis & CKD
Long-term dialysis and acquired cystic kidney disease in patients with chronic kidney disease raise RCC risk.
Occupational Exposure
Exposure to trichloroethylene, cadmium, and asbestos in industrial settings increases kidney cancer risk.
Incidental Discovery — Routine Ultrasound Saves Lives
Many kidney cancers are discovered incidentally during abdominal ultrasound or CT done for other reasons. At this early stage, surgical cure is highly achievable. Dr. Gupta recommends imaging in anyone with persistent haematuria or unexplained flank pain.
Ready to Take the First Step?
Book a consultation with Dr. Novak Gupta today. Expert oncology care is just a call away.